Langanzeige der Metadaten
DC Element | Wert | Sprache |
---|---|---|
dc.contributor.author | Bobers, Jens | - |
dc.contributor.author | Hahn, Lisa Katharina | - |
dc.contributor.author | Averbeck, Tobias | - |
dc.contributor.author | Brunschweiger, Andreas | - |
dc.contributor.author | Kockmann, Norbert | - |
dc.date.accessioned | 2024-03-01T12:27:55Z | - |
dc.date.available | 2024-03-01T12:27:55Z | - |
dc.date.issued | 2022-03-11 | - |
dc.identifier.uri | http://hdl.handle.net/2003/42369 | - |
dc.identifier.uri | http://dx.doi.org/10.17877/DE290R-24206 | - |
dc.description.abstract | The combination of lab automation and design of experiments for the execution of screening experiments increases productivity and reduces error-prone manual work. A self-developed software tool allows for creating fractional-factorial experimental design (FFED). Application of FFED on the screening of a Suzuki-Miyaura cross-coupling leads to a 93 % reduced design compared to full-factorial design. The resulting regression model qualitatively shows the positive effect of educt concentrations, time, and temperature and reveals the decrease in conversion at high base concentrations. | en |
dc.language.iso | en | de |
dc.relation.ispartofseries | Chemie - Ingenieur - Technik;94(5) | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | de |
dc.subject | Design of experiments | en |
dc.subject | Lab automation | en |
dc.subject | Reaction optimization | en |
dc.subject | Suzuki-Miyaura reaction | en |
dc.subject.ddc | 660 | - |
dc.title | Reaction optimization of a Suzuki‐Miyaura cross‐coupling using design of experiments | en |
dc.type | Text | de |
dc.type.publicationtype | Article | de |
dc.subject.rswk | Versuchsplanung | de |
dc.subject.rswk | Labortechnik | de |
dc.subject.rswk | Automation | de |
dc.subject.rswk | Reaktionsoptimierung | de |
dc.subject.rswk | Suzuki-Miyaura-Reaktion | de |
dcterms.accessRights | open access | - |
eldorado.secondarypublication | true | de |
eldorado.secondarypublication.primaryidentifier | https://doi.org/10.1002/cite.202100194 | de |
eldorado.secondarypublication.primarycitation | Bobers, J., Hahn, L.K., Averbeck, T., Brunschweiger, A. and Kockmann, N. (2022), Reaction Optimization of a Suzuki-Miyaura Cross-Coupling Using Design of Experiments. Chemie Ingenieur Technik, 94: 780-785. https://doi.org/10.1002/cite.202100194 | en |
Enthalten in den Sammlungen: | Arbeitsgruppe Apparatedesign |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
---|---|---|---|---|
Chemie Ingenieur Technik - 2022 - Bobers - Reaction Optimization of a Suzuki‐Miyaura Cross‐Coupling Using Design of.pdf | DNB | 4.21 MB | Adobe PDF | Öffnen/Anzeigen |
Diese Ressource ist urheberrechtlich geschützt. |
Diese Ressource wurde unter folgender Copyright-Bestimmung veröffentlicht: Lizenz von Creative Commons