Ramachandran, A. V.
|Title:||Oreocnide integrifolia (Gaud.)Miq. exhibits hypoglycemic and hypolipidemic potentials on streptozotocin diabetic rats|
|Other Titles:||a preliminary dose and duration dependent study|
|Abstract:||Oreocnide integrifolia (Gaud.)Miq (Urticaceae) leaves are used to alleviate diabetic symptoms in folk medicine in northeast India. In the present study, dose and duration dependent hypoglycemic potentials were evaluated in streptozotocin induced diabetic rats. Administration of aqueous leaf extract (100, 250, 500 and 750 mg/kg body weight orally once daily) to diabetic rats reduced glycemic levels by 56 % by 4 weeks of treatment and was comparable to standard reference drug Metformin. The experimental data also revealed significant improvement in lowering lipid profile, Urea, Creatinine, Hb, HbA1c and insulin levels. The present study clearly demonstrates hypoglycemic and hypolipidemic potential of Oreocnide integrifolia leaf extract.|
|Appears in Collections:||Original Articles|
Files in This Item:
|Oreocnide_060509_proof.pdf||DNB||150.88 kB||Adobe PDF||View/Open|
This item is protected by original copyright
All resources in the repository are protected by copyright.