Authors: | Aikawa, Júlia Bonatto, Sandro José Ribeiro Freire dos Santos, Leandro Habu, Sascha Prado, Karin Braun Rubel, Rosália Soccol, Carlos Ricardo Soccol, Vanete Thomaz Torres, Maria Fernanda Yamaguchi, Adriana Aya Zanatta, Ana Lucia |
Title: | Cordyceps sinensis biomass produced by submerged fermentation in high-fat diet feed rats normalizes the blood lipid and the low testosterone induced by diet |
Language (ISO): | en |
Abstract: | This study investigated the effect of Cordyceps sinensis biomass supplementation obtained from submerged fermentation on blood lipid and low testosterone induced by high-fat diet (HFD). The experiments were carried out using a long-term intake of HFD and HFD plus Simvastatin or C. sinensis (4 months). Our results show that plasma cholesterol, triglycerides and LDL were decreased by Cordyceps sinensis biomass supplementation (CSBS). A longterm intake of HFD caused a significant liver damage which has been reverted by CSBS. CSBS normalized decreasing testosterone levels observed in high-fat diet feed rats. All these findings lead us to suggest that C. sinensis was able to decrease blood lipid concentration, increase hepatoprotective activity and normalize testosterone levels. |
Subject Headings: | Cordyceps sinensis high-fat diet hypolipidemic effect testosterone |
URI: | http://hdl.handle.net/2003/30314 http://dx.doi.org/10.17877/DE290R-10558 |
Issue Date: | 2013-05-13 |
Appears in Collections: | Original Articles |
Files in This Item:
File | Description | Size | Format | |
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Freire dos Santos_03122012_proof.pdf | DNB | 324.35 kB | Adobe PDF | View/Open |
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