Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Muhammad, Aminu | - |
dc.contributor.author | Sirat, Hasnah Mohd | - |
dc.date.accessioned | 2014-03-11T13:57:41Z | - |
dc.date.available | 2014-03-11T13:57:41Z | - |
dc.date.issued | 2013-09-13 | - |
dc.identifier.issn | 1611-2156 | - |
dc.identifier.uri | http://hdl.handle.net/2003/32961 | - |
dc.identifier.uri | http://dx.doi.org/10.17877/DE290R-7476 | - |
dc.description.abstract | Chemical investigation of the stem bark of Bauhinia rufescens resulted in the isolation of a new cyanoglucoside and menisdaurin from methanol extract and oxepin from petroleum ether extract. The isolated compounds were tested for their anti-inflammatory potentials based on the cyclooxygenase-2 enzyme (COX-2) model. Cyanoglucoside exhibited the highest activity among the compounds with an inhibition activity of 49.34 % at 100 μM (IC50 0.46 μM) compared to the positive control, indomethacin (79.20 %, IC50 0.24 μM). | en |
dc.language.iso | en | - |
dc.relation.ispartofseries | EXCLI Journal ; Vol. 12, 2013 | en |
dc.subject | COX-2 | de |
dc.subject | Bauhinia rufescens | en |
dc.subject | phytochemicals | en |
dc.subject.ddc | 610 | - |
dc.title | COX-2 inhibitors from stem bark of Bauhinia rufescens Lam. (Fabaceae) | en |
dc.type | Text | - |
dc.type.publicationtype | article | - |
dcterms.accessRights | open access | - |
eldorado.dnb.zdberstkatid | 2132560-1 | - |
Appears in Collections: | Original Articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Sirat_13092013_proof.pdf | DNB | 197.08 kB | Adobe PDF | View/Open |
This item is protected by original copyright |
This item is protected by original copyright rightsstatements.org