Authors: | Crespo Yanguas, Sara Willebrords, Joost Maes, Michaël da Silva, Tereza Cristina Veloso Alves Pereira, Isabel Cogliati, Bruno Zaidan Dagli, Maria Lucia Vinken, Mathieu |
Title: | Connexins and pannexins in liver damage |
Language (ISO): | en |
Abstract: | Connexins and pannexins are key players in the control of cellular communication and thus in the maintenance of tissue homeostasis. Inherent to this function these proteins are frequently involved in pathological processes. The present paper reviews the role of connexins and pannexins in liver toxicity and disease. As they act both as sensors and effectors in these deleterious events connexins and pannexins could represent a set of novel clinical diagnostic biomarkers and drug targets. |
Subject Headings: | connexin pannexin acute liver injury steatosis hepatitis cholestasis fibrosis liver cancer |
URI: | http://hdl.handle.net/2003/35077 http://dx.doi.org/10.17877/DE290R-17125 |
Issue Date: | 2016-02-25 |
Rights link: | http://creativecommons.org/licenses/by/4.0/ |
Appears in Collections: | Review Articles |
Files in This Item:
File | Description | Size | Format | |
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Vinken_25022016_proof.pdf | DNB | 215.27 kB | Adobe PDF | View/Open |
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