Autor(en): Fathizadeh, Hadis
Milajerdi, Alireza
Reiner, Željko
Kolahdooz, Fariba
Asemi, Zatollah
Titel: The effects of L-carnitine supplementation on glycemic control
Sonstige Titel: a systematic review and meta-analysis of randomized controlled trials
Sprache (ISO): en
Zusammenfassung: The findings of trials investigating the effect of L-carnitine administration on glycemic control are controversial. This meta-analysis of randomized controlled trials (RCTs) was performed to explore the effects of L-carnitine intake on glycemic control. Two authors independently searched electronic databases including MEDLINE, EMBASE, Cochrane Library, Web of Science, PubMed and Google scholar from 1990 until February 2019, in order to find relevant RCTs. 37 studies with 44 effect sizes met the inclusion criteria and were eligible for the meta-analysis. L-carnitine supplementation resulted in a significant reduction in fasting plasma glucose (FPG) (WMD: -4.57; 95 % CI: -6.88, -2.25), insulin (WMD: -1.21; 95 % CI: -1.85, -0.57), homeostatic model assessment for insulin resistance (HOMA-IR) (WMD: -0.67; 95 % CI: -0 .90, -0.44) and HbA1C concentrations (WMD: -0.30; 95 % CI: -0.47, -0.13). L-Carnitine supplementation significantly reduced FPG, insulin, HOMA-IR, and HbA1c levels.
Schlagwörter: L-carnitine
Glycemic control
Insulin resistance
Meta-analysis
URI: http://hdl.handle.net/2003/39038
http://dx.doi.org/10.17877/DE290R-20957
Erscheinungsdatum: 2019-08-19
Rechte (Link): https://creativecommons.org/licenses/by/4.0/
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