Brunnert, MarcusMüller, OliverUrfer, Wolfgang2004-12-062004-12-062000http://hdl.handle.net/2003/501110.17877/DE290R-5381In this paper we describe the principles of polymerase chain reaction (PCR) and its expanding use in molecular genetic research and molecular medicine. A short introduction of exemplary applications of the PCR is connected with a discussion of the lack of PCR accuracy. We give a statistical model for the PCR and discuss estimation methods in order to quantify the lack of PCR accuracy.enUniversitätsbibliothek Dortmundbranching processestimation of the mutation rate.lack of PCR accuracypolymerase chain reaction310report