Muhammad, AminuSirat, Hasnah Mohd2014-03-112014-03-112013-09-131611-2156http://hdl.handle.net/2003/3296110.17877/DE290R-7476Chemical investigation of the stem bark of Bauhinia rufescens resulted in the isolation of a new cyanoglucoside and menisdaurin from methanol extract and oxepin from petroleum ether extract. The isolated compounds were tested for their anti-inflammatory potentials based on the cyclooxygenase-2 enzyme (COX-2) model. Cyanoglucoside exhibited the highest activity among the compounds with an inhibition activity of 49.34 % at 100 μM (IC50 0.46 μM) compared to the positive control, indomethacin (79.20 %, IC50 0.24 μM).enEXCLI Journal ; Vol. 12, 2013COX-2Bauhinia rufescensphytochemicals610article (journal)