Kikuchi, KunimiSaadat, Mostafa2008-06-172008-06-172005-10-101611-2156http://hdl.handle.net/2003/2565310.17877/DE290R-340Expressions of protein phosphatases 1a (PP1a), and 1g1 (PP1g1) was determined in cultured rat ascites hepatoma cell lines (AH-13, AH-109A) and in the normal rat hepatocyte cell line RLN-B2 by Northern blot analysis. High levels of PP1a mRNA expression were observed only in the hepatoma cells. In RLN-B2 cells only PP1g1 mRNA was increased compared to normal rat liver. In all cell types, mRNA levels of PP1g1 decreased as a function of harvest time. The present data show that PP1a mRNA is expressed at high levels in hepatoma cells in vivo, but rapidly decreased under critical nutritional conditions.enEXCLI Journal ; Vol. 4, 2005ascites hepatomacell culturePP1aPP1g1protein phosphatase610article (journal)