Jiang, Jian-GouTian, Ying-JuanYang, LiZhu, Liang2011-05-172011-05-172011-05-17http://hdl.handle.net/2003/2775010.17877/DE290R-1161Blumea megacephala essential oil, obtained through steam distillation of samples collected from the Shiwang Mountains in Guangxi Province, China, was analyzed using GC-FID and GC-MS. Among the 65 compounds identified in the oil, the main compounds were borneol (13.6 %), β-caryophyllene (9.56 %), germacrene D (9.09 %), sabinene (6.37 %), and α-humulene (4.78 %). Antimicrobial activity revealed that the essential oil (1000 μg/disc) has promising antimicrobial effects against several pathogens, giving satisfactory inhibition zone diameter values (21.5, 21.6, 23.4, 23.8, 21.9) and MIC values (125, 125, 62.5, 125, 125 μg/ml) against Gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli), Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus), and yeast (Hansenula anomala). Antioxidant and antimicrobial activities were correlated with chemical composition.enEXCLI Journal ; Vol. 10, 2011antimicrobial activityBlumea megacephalaessential oilGC/MS610article (journal)