Ehlhardt, JensAhmad, AfaqWolf, IngaEngell, Sebastian2025-01-312025-01-312023-04-03http://hdl.handle.net/2003/4339410.17877/DE290R-25226In this work, the optimal time-varying allocation of steam in a large-scale industrial isocyanate production process is addressed. This is a problem that falls into the category of real-time optimization (RTO). The application of RTO in practice faces two problems: First the available rigorous process models may not be suitable for use in real-time connected to the process. Second, there is always a mismatch between the predictions of the model and the behavior of the real plant. We address the first problem by training a neural net model as a surrogate to data generated by a rigorous simulation model so that the model is simple to implement and short execution times result. The second problem is tackled by adapting the optimization problem based on measured data such that convergence to the optimal operating conditions for the real plant is achieved.enChemie - Ingenieur - Technik; 95(7)https://creativecommons.org/licenses/by/4.0/Isocyanate productionModifier adaptation with quadratic approximationReal-time optimizationSurrogate models660ResearchArticle