Powder bed fusion (PBF) processes enable the manufacturing of complex components in a time- and cost-efficient manner. Especially lattice structures are currently focused since they show varying mechanical properties, including different deformation and damage behaviors, which can be used to locally tailor the mechanical behavior. However, the present process-structure-property relationships are highly complex and have to be understood in detail in order to enable an implementation of PBF man...

This article aims to analyse the difficulties Central American refugee women face when applying for refugee protection in Mexico and how they negotiate survival during this process. Claiming refugee protection is an important legal mechanism to ensure survival, but managing this process successfully is difficult, not only because of the bureaucratic complexities but also because of structural and political constraints. Research has addressed the difficulties migrant women face while in transi...

The study and design of novel molecular materials, miniaturized molecular switches and sensors, is propelled by the investigation of electronically-labile systems. This property enables molecules to interconvert between distinct (meta-)stable electronic states. A prominent group of bistable molecular systems is represented by cobalt-based valence tautomer transition-metal complexes, which can be switched between tautomeric forms by external stimuli such as temperature, pressure, or irradiat...

The dynamics of congruency effects in conflict tasks can be analyzed by means of delta plots which depict the reaction-time differences between incongruent and congruent conditions across the quantiles of the reaction-time distributions. Delta plots exhibit a variety of different shapes. Here we test the hypothesis that staggered onsets of processing task-relevant and task-irrelevant features for response selection (together with a declining influence of the irrelevant feature) produce such v...

One of the main goals of the teacher and the school system as a whole is to close learning gaps and support children with difficulties in learning. The identification of those children as well as the monitoring of their progress in learning is crucial for this task. The derivation of comparative standards that can be applied well in practice is a relevant quality criterion in this context. Continuous normalization is particularly useful for progress monitoring tests that can be conducted at d...

Helicity is an archetypal structural motif of many biological systems and provides a basis for molecular recognition in DNA. Whilst artificial supramolecular hosts are often helical, the relationship between helicity and guest encapsulation is not well understood. We report a detailed study on a significantly coiled-up Pd2L4 metallohelicate with an unusually wide azimuthal angle (∼176°). Through a combination of NMR spectroscopy, single-crystal X-ray diffraction, trapped ion mobility mass spe...

Glucose-transporter (GLUT)-inhibitors, like Glutor and Glupin, effectively inhibit the proliferation of different tumor cells, making them potential candidates for cancer therapies. Therefore, assessing the impact of GLUT-inhibitors on NK cell function is crucial, as these cells play an important role in anti-tumor response. Seahorse analysis of the energetic phenotype of NK cells treated with Glutor or Glupin showed decreased glycolysis. To further examine the effect of both inhibitors on NK...

Although more than a hundred thousand protein structures are registered in the Protein Data Bank, there are still more open questions than answers. One of these proteins that have captivated researchers for decades is ribonucleotide reductase, short RNR. Due to its central role in every living organism, RNR has been the focus of research on several occasions, but many questions remain unanswered despite numerous studies. Moreover, information about RNR structure in its natural environment, na...

Krebserkrankungen zählen neben Herz-Kreislauferkrankungen immer noch zu den häufigsten frühzeitigen Todesarten weltweit. Ein wichtiges Ziel der modernen Tumortherapie ist daher die Entwicklung neuartiger Wirkstoffe und Diagnostika. Dabei kann auch die Formulierung dieser Stoffe einen signifikanten Einfluss auf die Effizienz einer Therapie bzw. eines diagnostischen Verfahrens besitzen. Besonders vernetzte polymere Nanopartikel sind dabei seit einigen Jahrzehnten in den Fokus der Forschend...

Die folgenschwere Hochwasserkatastrophe im Juli 2021 verdeutlicht die Notwendigkeit zur Verbesserung der Hochwasser- und Überflutungsvorsorge in den betroffenen Regionen des Ahrtals. Ziel der Arbeit ist es, unter Verwendung einer multikriteriellen Bewertungsmethodik auf regionaler Maßstabsebene, potentielle Standorte für Hochwasserrückhaltebecken und Versiegelungsverbotszonen zu identifizieren. Durch eine Erhöhung der Wasserspeicherkapazitäten in der Landschaft und eine Reduzierung der weiter...

We consider the Fokker-Planck equation (FPE) for the orientation proba­bility density of fiber suspensions. Using the continuous Galerkin method, we express the numerical solution in terms of Lagrange basis functions that are associated with N nodes of a computational mesh for a domain in the 3D physical space and M nodes of a mesh for the surface of a unit sphere representing the configuration space. The NM time-dependent unknowns of our finite element approximations are probabilities corres...

Numerical simulation of three field formulations of incompressible flow problems is of interest for many industrial applications, for instance macroscopic modeling of Bing-ham, viscoelastic and multiphase flows, which usually consists in supplementing the mass and momentum equations with a differential constitutive equation for the stress field. The variational formulation rising from such continuum mechanics problems leads to a three field formulation with saddle point structure. The solvability o...

The DELTA facility is a synchrotron light source located in Dortmund, Germany. Here, the TU Dortmund University operates a 1.5 GeV storage ring supplying radiation ranging from the THz to the hard X-ray regime for experiments in chemistry, biochemistry, solid-state physics and materials science. The ring is equipped with a slow orbit feedback (SOFB) that corrects the transverse orbit position using a set of steerer magnets. The orbit correction software acts as the feedback's controller....

Students’ math-related expectancies of success and subjective task values are important predictors of their educational and career choices, such as students’ decisions to persist in or drop out of math-intensive study programs in the fields of science, technology, engineering, and mathematics (STEM). Introductory math courses are often a gatekeeper to further engagement and success in STEM fields because students often experience low levels of motivation and achievement in such courses. Howev...