Eldorado - Repositorium der TU Dortmund

Ressourcen aus und für Forschung, Lehre und Studium

Bei diesem Service handelt es sich um das Institutionelle Repositorium der Technischen Universität Dortmund. Hier werden Ressourcen aus und für Lehre, Studium und Forschung gespeichert, erschlossen und der Öffentlichkeit zugänglich gemacht.

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Aktuellste Veröffentlichungen

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    Exploring the multifaceted Dbf4-dependent kinase from temporal, spatial, and substrate repertoire perspectives
    (Springer Science and Business Media LLC, 2026-06-23) Galanti, Lorenzo; Pfander, Boris
    The Dbf4‑dependent kinase (DDK), composed of the catalytic subunit Cdc7 and the regulatory subunit Dbf4, is a serine/threonine kinase traditionally defined as an essential activator of DNA replication. Here, we review DDK function from three complementary perspectives: its temporal regulation during the cell cycle, its spatial organization on chromosomes, and its expanding substrate repertoire. These perspectives reveal that DDK acts beyond DNA replication, targeting proteins involved in chromosome segregation, DNA damage responses and homologous recombination. Together, they redefine DDK as multifunctional genome integrity kinase which coordinates cell cycle progression and genome stability offering a unique therapeutic potential in cancer therapy.
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    Probabilistic modelling of material properties based on structural design and testing standards and its impact on the assessment of structural service life
    (Springer Science and Business Media LLC, 2026-03-19) Faghfouri, Saeideh; Feiri, Tânia; Ricker, Marcus; Strauss, Alfred
    The reliability of engineering structures and infrastructure is a critical requirement to ensure a continuous functionality throughout their expected service life. The lifespan extension of concrete structures—especially those belonging to critical infrastructure—is vital to the sustainability and resilience of the whole built environment. This investigation explores the potential to extend the service lifetime of concrete structures by considering the role of modern design codes and conformity standards on concrete production in combination with reliability-based safety concepts applied to the resistance side. The study demonstrates how evaluation criteria derived from empirical concrete samples influence the service life of structures and, in consequence, the safety format established in international codes. The results suggest that by considering measures of concrete variability—as the coefficients of variation—and integrating them into a quality control system, hidden safety margins can be identified and, ultimately, activated to extend the service lifetime of structures. Therefore, this investigation contributes to the sustainable development of infrastructure ensuring that future demands on infrastructure can be met while maintaining high safety standards.
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    Soziologische Modellierung nachhaltiger Transformation
    (2026) Philipp, Marlon; Weyer, Johannes; Sommer, Bernd
    Die Dissertation untersucht am Beispiel des Ruhrgebiets, wie eine nachhaltige Transformation des Mobilitätssektors sozialwissenschaftlich analysiert und gestaltet werden kann. Hierzu wird ein soziologisches Modell nachhaltiger Transformation (SMNT) entwickelt, das bestehende Nachhaltigkeits- und Transformationsmodelle in einem Mehrebenenansatz integriert. Eine Literaturanalyse zeigt, dass der deutsche Mobilitätssektor zentrale Nachhaltigkeitsziele verfehlt. Im empirischen Teil werden die Ergebnisse einer Befragung von 10.782 Universitätsangehörigen im Ruhrgebiet in die agentenbasierte Verkehrssimulation (MATSim) integriert. Die Befragung zeigt eine Diskrepanz zwischen der Nutzung des öffentlichen Verkehrs und den Präferenzen für individuelle Mobilität; zudem werden fünf Akteurstypen identifiziert. Mittels der Simulation werden fünf nachhaltige Governance-Optionen analysiert. Die Ergebnisse zeigen, dass insbesondere eine Steigerung des Fahrradkomforts sowohl die soziale als auch die ökologische Nachhaltigkeit verbessern kann.
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    Amtliche Mitteilungen der Technischen Universität Dortmund Nr. 20/2026
    (Technische Universität Dortmund, 2026-09-22)
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    In defense of ‘surveillance capitalism’
    (Springer Science and Business Media LLC, 2024-10-16) Königs, Peter
    Critics of Big Tech often describe ‘surveillance capitalism’ in grim terms, blaming it for all kinds of political and social ills. This article counters this pessimistic narrative, offering a more favorable take on companies like Google, YouTube, and Twitter/X. It argues that the downsides of surveillance capitalism are overstated, while the benefits are largely overlooked. Specifically, the article examines six critical areas: i) targeted advertising, ii) the influence of surveillance capitalism on politics, iii) its impact on mental health, iv) its connection with government surveillance, v) its effects on the rule of law and social trust, and vi) privacy concerns. For each area, it will be argued that concerns about surveillance capitalism are unfounded or exaggerated. The article also explores some benefits of the services provided by these technology companies and concludes with a discussion of the practical implications. Throughout, the article draws on empirical evidence relating to the societal and political impact of digital technologies.