Exercise reduces systemic immune inflammation index (SII) in childhood cancer patients

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dc.contributor.authorWinker, Matteo
dc.contributor.authorStössel, Sandra
dc.contributor.authorNeu, Marie Astrid
dc.contributor.authorLehmann, Nadine
dc.contributor.authorEl Malki, Khalifa
dc.contributor.authorParet, Claudia
dc.contributor.authorJoisten, Niklas
dc.contributor.authorBloch, Wilhelm
dc.contributor.authorZimmer, Philipp
dc.contributor.authorFaber, Jörg
dc.date.accessioned2022-05-11T13:24:35Z
dc.date.available2022-05-11T13:24:35Z
dc.date.issued2021-12-03
dc.description.abstractWhile exercise and physical activity have been suggested to reduce mortality and symptoms in cancer, knowledge on these associations in patients with childhood cancer (CCPs) is sparse. Anti-inflammatory properties of exercise might mediate these beneficial effects. We investigated the influence of exercise on the inflammation markers neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic-immune-inflammation index (SII) and associations to patient-reported-outcomes in CCPs in a randomized-controlled trial. Results show associations between inflammation markers and patient-reported outcomes. Compared to the control group, SII was significantly reduced following exercise (p=0.036). Anti-inflammatory effects of exercise are also present in CCPs and may underlie exercise-induced benefits on symptoms. Clinical Trial Registration Number: NCT02612025en
dc.identifier.urihttp://hdl.handle.net/2003/40900
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-22756
dc.language.isoende
dc.relation.ispartofseriesSupportive care in cancer;Bd 30. 2021, Heft 4, S. 2905-2908
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectTumor entitiesen
dc.subjectCellular inflammationen
dc.subjectPediatric oncologyen
dc.subjectResistance trainingen
dc.subjectEndurance trainingen
dc.subject.ddc796
dc.subject.rswkKindde
dc.subject.rswkOnkologiede
dc.subject.rswkSportde
dc.titleExercise reduces systemic immune inflammation index (SII) in childhood cancer patientsen
dc.typeTextde
dc.type.publicationtypearticlede
dcterms.accessRightsopen access
eldorado.secondarypublicationtruede
eldorado.secondarypublication.primarycitationSupportive care in cancer. Band 30. 2021, Heft 4, Seiten 2905-2908de
eldorado.secondarypublication.primaryidentifierhttps://doi.org/10.1007/s00520-021-06719-3de

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