Selective monosubstitution on a trichlorosilane with highly reactive organolithium compounds in a microflow reactor

Abstract

Organolithium compounds have been used successfully in flow chemistry since the recent past. Most of the studies dealt with the use in halogen-lithium exchanges. So far, however, there has been a lack of use in substitution reactions. The use of flow microreactors makes the highly reactive organolithium compounds more controllable and thus creates new synthetic possibilities.

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Keywords

Organosilanes, Substitutions, Selectivity, Microreactor, Continuous flow

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