A primer on building life-like systems

dc.contributor.authorVibhute, Mahesh A.
dc.contributor.authorMutschler, Hannes
dc.date.accessioned2023-10-26T13:54:13Z
dc.date.available2023-10-26T13:54:13Z
dc.date.issued2022-12-08
dc.description.abstractThe quest to understand life and recreate it in vitro has been undertaken through many different routes. These different approaches for experimental investigation of life aim to piece together the puzzle either by tracing life's origin or by synthesizing life-like systems from non-living components. Unlike efforts to define life, these experimental inquiries aim to recapture specific features of living cells, such as reproduction, self-organization or metabolic functions that operate far from thermodynamic equilibrium. As such, these efforts have generated significant insights that shed light on crucial aspects of biological functions. For observers outside these specific research fields, it sometimes remains puzzling what properties an artificial system would need to have in order to be recognized as most similar to life. In this Perspective, we discuss properties whose realization would, in our view, allow the best possible experimental emulation of a minimal form of biological life.en
dc.identifier.urihttp://hdl.handle.net/2003/42174
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-24008
dc.language.isoende
dc.relation.ispartofseriesChemSystemsChem;5(1)
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/de
dc.subjectSynthetic cellsen
dc.subjectOrigin of lifeen
dc.subjectSynthetic biologyen
dc.subjectSelf-replicationen
dc.subjectMolecular evolutionen
dc.subject.ddc570
dc.subject.ddc540
dc.titleA primer on building life-like systemsen
dc.typeTextde
dc.type.publicationtypeArticlede
dcterms.accessRightsopen access
eldorado.secondarypublicationtruede
eldorado.secondarypublication.primarycitationVibhute, M. A., Mutschler, H., ChemSystemsChem 2023, 5, e202200033.de
eldorado.secondarypublication.primaryidentifierDOI: https://doi.org/10.1002/syst.202200033de

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