Dielectric study of the viscous and glassy states of a binary, nifedipine-based pharmaceutical alloy

Abstract

An equimolar mixture of nifedipine and acetaminophen was studied in its supercooled liquid and in its glassy state using dielectric spectroscopy. It is found that this alloy is characterized by a relatively large steepness index m = 83. The low-temperature relaxation of pure nifedipine is studied and compared with that of the mixture.