A finite sample comparison of nonparametric estimates of the effective dose in quantal bioassay
Loading...
Date
2008-11-26T14:31:32Z
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
To estimate the effective dose level ED in the common binary response model, several
parametric and nonparametric estimators have been proposed in the literature. In the present paper, we focus on nonparametric methods and present a detailed numerical comparison of four different approaches to estimate the ED nonparametrically. The methods are briefly reviewed and their finite sample properties are studied by means of a detailed simulation study. Moreover, a data example is presented to illustrate the different concepts.
Description
Table of contents
Keywords
Binary response model, Effective dose level, Isotonic regression, Local linear regression, Nonparametric regression, Order restricted inference