Authors: | Kikuchi, Kunimi Saadat, Mostafa |
Title: | Expression of the protein phosphatases PP1a and PP1g1 in rat ascites hepatoma cell lines and in rat hepatocyte cell line |
Language (ISO): | en |
Abstract: | Expressions of protein phosphatases 1a (PP1a), and 1g1 (PP1g1) was determined in cultured rat ascites hepatoma cell lines (AH-13, AH-109A) and in the normal rat hepatocyte cell line RLN-B2 by Northern blot analysis. High levels of PP1a mRNA expression were observed only in the hepatoma cells. In RLN-B2 cells only PP1g1 mRNA was increased compared to normal rat liver. In all cell types, mRNA levels of PP1g1 decreased as a function of harvest time. The present data show that PP1a mRNA is expressed at high levels in hepatoma cells in vivo, but rapidly decreased under critical nutritional conditions. |
Subject Headings: | ascites hepatoma cell culture PP1a PP1g1 protein phosphatase |
URI: | http://hdl.handle.net/2003/25653 http://dx.doi.org/10.17877/DE290R-340 |
Issue Date: | 2005-10-10 |
Appears in Collections: | Original Articles |
Files in This Item:
File | Description | Size | Format | |
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Saadat11-05proof.pdf | DNB | 240.92 kB | Adobe PDF | View/Open |
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