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  4. Lehrstuhl Statistik mit Anwendungen im Bereich der Ingenieurwissenschaften
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dc.contributor.authorHartung, Joachim-
dc.contributor.authorKnapp, Guido-
dc.date.accessioned2010-07-28T16:01:12Z-
dc.date.available2010-07-28T16:01:12Z-
dc.date.issued2010-07-28-
dc.identifier.urihttp://hdl.handle.net/2003/27314-
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-14531-
dc.description.abstractIn a thorough and extensive simulation study, we investigate the practical properties of repeated confidence intervals and point estimates for the standardized difference of normal means in adaptive group sequential trials. The theoretical foundations have been described in Hartung and Knapp (2009, 2010). In the simulation study, we consider an adaptive three-stage Pocock (1977)-type design for planning and showing noninferiority and an adaptive five-stage O'Brien-Fleming (1979)-type design for planning and showing superiority.en
dc.language.isoende
dc.subjectPocock-type designen
dc.subjectO'Brien-Fleming-type designen
dc.subjectnoninferiorityen
dc.subjectsuperiorityen
dc.subjectrepeated confidence intervalsen
dc.subject.ddc310-
dc.titleAdaptive Group Sequential Trials with the Standardized Mean Difference as Effect Sizeen
dc.title.alternativeResults of a Simulation Studyen
dc.typeTextde
dc.type.publicationtypepreprintde
dcterms.accessRightsopen access-
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