Authors: Kiatfuengfoo, Rachada
Prachayasittikul, Supaluk
Prachayasittikul, Virapong
Ruchirawat, Somsak
Suksrichavalit, Thummaruk
Treeratanapiboon, Lertyot
Worachartcheewan, Apilak
Title: Bioactive 4-hydroxycinnamide and bioactivities of Polyalthia cerasoides
Language (ISO): en
Abstract: Constituents from Polyalthia cerasoides, stem bark methanol extract, were previously documented. This study reports the first isolation of bioactive N-(4-hydroxy-β-phenethyl)-4-hydroxycinnamide (1) from ethyl acetate extract of the plant species including stigmasterol and a mixture of triterpenes from hexane and dichloromethane extracts. Trace essential elements were found in the hexane extract in ppm level. The plant extracts were evaluated for their antimicrobial and antioxidative activities. The dichloromethane extract displayed the highest activity against Corynebacterium diphtheriae NCTC 10356 with MIC of 32 μg/mL, as well as, the highest SOD activity with an IC50 of 4.51 μg/mL.
Subject Headings: 4-hydroxycinnamide
antimicrobials
antioxidants
Polyalthia cerasoides
trace elements
URI: http://hdl.handle.net/2003/27745
http://dx.doi.org/10.17877/DE290R-1115
Issue Date: 2011-05-17
Appears in Collections:Original Articles

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