Authors: Ahmad, Shiekh Tanveer
Asiaf, Asia
Aslam, Mohammad
Bhat, Jalal Uddin
Khanam, Razia
Mujeeb, Mohammad
Nizami, Qudsia
Parray, Shabir Ahmad
Siddiqui, Aisha
Umar, Sadiq
Title: Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice
Language (ISO): en
Abstract: The aim of the present study was to evaluate the anticonvulsant effect of whole plant extracts of Melissa parviflora using MES and PTZ induced seizures models. The dried whole plant was subjected to extraction in methanol and water. The extracts were subjected to phytochem-ical tests and the carbohydrate, flavonols, coumarins, glycosides and steroid were found to be present. The methanolic and aqueous extracts of the plant of Melissa parviflora were observed for their anticonvulsant activity by Maximal Electroshock seizures (MES) test and Pentylene-tetrazole (PTZ) test using Swiss albino mice. Both the extracts showed significant activity in MES and PTZ induced convulsions in comparison to control. From the literature surveys as well experiments performed, it can be said that Melissa parviflora does pose anticonvulsant property.
Subject Headings: anticonvulsant effects
maximal electroshock
Melissa parviflora
Issue Date: 2012-09-19
Appears in Collections:Original Articles

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