Authors: | Ahmad, Shiekh Tanveer Asiaf, Asia Aslam, Mohammad Bhat, Jalal Uddin Khanam, Razia Mujeeb, Mohammad Nizami, Qudsia Parray, Shabir Ahmad Siddiqui, Aisha Umar, Sadiq |
Title: | Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice |
Language (ISO): | en |
Abstract: | The aim of the present study was to evaluate the anticonvulsant effect of whole plant extracts of Melissa parviflora using MES and PTZ induced seizures models. The dried whole plant was subjected to extraction in methanol and water. The extracts were subjected to phytochem-ical tests and the carbohydrate, flavonols, coumarins, glycosides and steroid were found to be present. The methanolic and aqueous extracts of the plant of Melissa parviflora were observed for their anticonvulsant activity by Maximal Electroshock seizures (MES) test and Pentylene-tetrazole (PTZ) test using Swiss albino mice. Both the extracts showed significant activity in MES and PTZ induced convulsions in comparison to control. From the literature surveys as well experiments performed, it can be said that Melissa parviflora does pose anticonvulsant property. |
Subject Headings: | anticonvulsant effects maximal electroshock Melissa parviflora pentylene-tetrazole |
URI: | http://hdl.handle.net/2003/29620 http://dx.doi.org/10.17877/DE290R-4921 |
Issue Date: | 2012-09-19 |
Appears in Collections: | Original Articles |
Files in This Item:
File | Description | Size | Format | |
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Bhat_Parray_20012012_proof.pdf | DNB | 54.51 kB | Adobe PDF | View/Open |
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