Authors: Rahman, Atiqur
Al-Reza, Sharif M.
Siddiqui, Shah Alam
Chang, Taehyun
Kang, Sun Chul
Title: Antifungal potential of essential oil and ethanol extracts of Lonicera japonica Thunb. against dermatophytes
Language (ISO): en
Abstract: The antifungal potential of essential oil and ethanolic leaf extracts of Lonicera japonica Thunb. was evaluated for controlling the growth of dermatophytes. The oil (1,000 ppm) and extracts (1,500 ppm) of L. japonica revealed 55.1–70.3 % and 40.1–65.5 % antidermatophytic effect against Microsporum canis KCTC 6348, 6349, 6591, Trichophyton rubrum KCTC 6345, 6352, 6375, Trichophyton mentagrophytes KCTC 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations ranging from 62.5-500 and 125-1,000 μg/ml. Also, the oil had strong detrimental effect on spore germination of all the tested dermatophytes as well as concentration and time-dependent kinetic inhibition of M. canis KCTC 6348. The results demonstrated that L. japonica oil and extracts could be potential sources of natural fungicides to protect human and animals from fungal infections.
Subject Headings: Lonicera japonica Thunb.
essential oil
ethanolic extracts
antidermatophytic activity
skin infectious fungal pathogens
Issue Date: 2014-04-28
Appears in Collections:Original Articles

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