Authors: Kumar, Vishal
Reddy, S. G. Eswara
Bhardwaj, Anuja
Dolma, Shudh Kirti
Kumar, Neeraj
Title: Larvicidal activity and structure activity relationship of cinnamoyl amides from Zanthoxylum armatum and their synthetic analogues against diamondback moth, Plutella xylostella
Language (ISO): en
Abstract: Cinnamoyl amides isolated from Zanthoxylum armatum (Rutaceae) and their synthetic analogues were tested for their insecticidal activity against the second instar larvae of diamondback moth, Plutella xylostella (L.) (Lepidoptera: Yponomeutidae) to determine the promising structures with insecticidal activity. Most of the test compounds showed promising activity against larvae of P. xylostella. However, the activities of different compounds varied depending on the presence of different substituents at various positions of both the aromatic rings A and B. Among the tested compounds, 8, N-(3-bromo-4-methoxyphenethyl)cinnamamide showed best larvicidal activity with an LC50 = 62.13 mg/L followed by 6, N-(3 ׳-bromophenethyl)cinnamamide (LC50=128.49 mg/L) and 2 N-(4 ׳-methoxyphenylethyl)cinnamamide (LC50 = 225.65 mg/L).
Subject Headings: cinnamoyl amides
structure activity relationship
larvicidal activity
Plutella xylostella
Issue Date: 2016-03-18
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