Full metadata record
DC FieldValueLanguage
dc.contributor.authorBabaie, Jalal-
dc.contributor.authorSayyah, Mohammad-
dc.contributor.authorGharagozli, Kourosh-
dc.contributor.authorMostafavi, Ehsan-
dc.contributor.authorGolkar, Majid-
dc.date.accessioned2017-08-28T12:24:31Z-
dc.date.available2017-08-28T12:24:31Z-
dc.date.issued2017-03-13-
dc.identifier.citationEXCLI Journal 2017;16:256-264en
dc.identifier.issn1611-2156-
dc.identifier.urihttp://hdl.handle.net/2003/36074-
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-18090-
dc.description.abstractEpilepsy is one of the most common neurologic disorders. Underlying cause of epilepsy is unknown in 60 % of the patients. Toxoplasma gondii is an intracellular parasite which is capable of forming tissue cysts in brain of chronically infected hosts including humans. Some epidemiological studies suggested an association between tox- oplasmosis and acquisition of epilepsy. In this study we determined seroprevalence of latent Toxoplasma infection in a population of Iranian epileptic patients. Participants were classified in three groups as Iranian epileptic patients (IEP, n = 414), non-epileptic patients who had other neurologic disorders (NEP, n = 150), and healthy people without any neurologic disorders (HP, n = 63). The presence of anti-Toxoplasma IgG antibodies and IgG titer in the sera were determined by ELISA method. Anti-T. gondii IgG seroprevalence obtained 35.3 %, 34.7 % and 38.1 % in IEP, NEP and HP, respectively. The seroprevalence rate was not significantly different among the three groups (P = 0.88). Anti-T. gondii IgG titer was 55.7 ± 78, 52.4 ± 74 and 69.7 ± 92 IU/ml in IEP, NEP and HP, respectively. There was not any statistically significant difference in the antibody titer between the study groups (P = 0.32). The rate of T. gondii infection in epileptic patients was not higher than non-epileptic patients and healthy people in the Iranian population.en
dc.language.isoen-
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/-
dc.subjectEpilepsyen
dc.subjectToxoplasma gondiien
dc.subjectIgGen
dc.subjectELISAen
dc.subjectSeroprevalenceen
dc.subject.ddc610-
dc.titleSeroepidemiological study of Toxoplasma gondii infection in a population of Iranian epileptic patientsen
dc.typeText-
dc.type.publicationtypearticle-
dcterms.accessRightsopen access-
eldorado.dnb.zdberstkatid2132560-1-
Appears in Collections:Original Articles

Files in This Item:
File Description SizeFormat 
Sayyah_13032017_proof.pdfDNB148.76 kBAdobe PDFView/Open


This item is protected by original copyright



This item is licensed under a Creative Commons License Creative Commons