Authors: Ebrahimi, Khadije
Majdi, Alireza
Baghaiee, Behrouz
Hosseini, Seyed Hojjat
Sadigh-Eteghad, Saeed
Title: Physical activity and beta-amyloid pathology in Alzheimer's disease
Other Titles: a sound mind in a sound body
Language (ISO): en
Abstract: Alzheimer's disease (AD) is the most common type of dementia worldwide. Since curative treatment has not been established for AD yet and due to heavy financial and psychological costs of patients’ care, special attention has been paid to preventive interventions such as physical activity. Evidence shows that physical activity has protective effects on cognitive function and memory in AD patients. Several pathologic factors are involved in AD-associated cognitive impairment some of which are preventable by physical activity. Also, various experimental and clinical studies are in progress to prove exercise role in the beta-amyloid (Aβ) pathology as a most prevailing hypothesis explaining AD pathogenesis. This study aims to review the role of physical activity in Aβ-related pathophysiology in AD.
Subject Headings: Physical activity
Alzheimer's disease
Issue Date: 2017-06-28
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Appears in Collections:Review Articles

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