Authors: Guo, Jiaqi
Tian, Changhao
Xu, Bing
Title: Biomaterials based on noncovalent interactions of small molecules
Language (ISO): en
Abstract: Unlike conventional materials that covalent bonds connecting atoms as the major force to hold the materials together, supramolecular biomaterials rely on noncovalent intermolecular interactions to assemble. The reversibility and biocompatibility of supramolecular biomaterials render them with diverse range of functions and lead to rapid development in the past two decades. This review focuses on the noncovalent and enzymatic control of supramolecular biomaterials, with the introduction to various triggering mechanism to initiate self-assembly. Representative applications of supramolecular biomaterials are highlighted in four categories: tissue engineering, cancer therapy, drug delivery, and molecular imaging. By introducing various applications, we intend to show enzymatic control and noncovalent interactions as a powerful tool for achieving spatiotemporal control of biomaterials both in vitro and in vivo for biomedicine.
Subject Headings: Noncovalent interactions
Supramolecular biomaterials
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Issue Date: 2020-08-05
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Provenance: IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund
Citation: Guo, J., Tian, C., & Xu, B. (2020). Biomaterials based on noncovalent interactions of small molecules. EXCLI Journal, 19, 1124-1140.
Appears in Collections:Review Articles 2020

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