Fluorescence microscopy studies on the fibrillation of IAPP at model and cellular lipid interfaces, from mechanism to potential strategies in type II diabetes mellitus
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Islet amyloid polypeptide (IAPP), Amyloid, Type II diabetes mellitus, Fibril formation, Protein aggregation, IAPP fragments, Giant unilamellar vesicles (GUVs), Raft membrane model systems, INS-1E cell line, Resveratrol, Advanced fluorescence microscopy, Confocal, two-photon excitation, High hydrostatic pressure (HHP), FT-IR spectroscopy, Atomic force microscopy (AFM), Cytotoxicity, WST-1 assay