Fluorescence microscopy studies on the fibrillation of IAPP at model and cellular lipid interfaces, from mechanism to potential strategies in type II diabetes mellitus

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dc.contributor.advisorWinter, Roland
dc.contributor.authorRadovan, Diana
dc.contributor.refereeRehage, Heinz
dc.date.accepted2009-10-08
dc.date.accessioned2009-10-21T10:16:59Z
dc.date.available2009-10-21T10:16:59Z
dc.date.issued2009-10-21T10:16:59Z
dc.identifier.urihttp://hdl.handle.net/2003/26463
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-15340
dc.identifier.urnurn:nbn:de:hbz:290-2003/26463-2
dc.language.isoen
dc.subjectIslet amyloid polypeptide (IAPP)en
dc.subjectAmyloiden
dc.subjectType II diabetes mellitusen
dc.subjectFibril formationen
dc.subjectProtein aggregationen
dc.subjectIAPP fragmentsen
dc.subjectGiant unilamellar vesicles (GUVs)en
dc.subjectRaft membrane model systemsen
dc.subjectINS-1E cell lineen
dc.subjectResveratrolen
dc.subjectAdvanced fluorescence microscopyen
dc.subjectConfocal, two-photon excitationen
dc.subjectHigh hydrostatic pressure (HHP)en
dc.subjectFT-IR spectroscopyen
dc.subjectAtomic force microscopy (AFM)en
dc.subjectCytotoxicityen
dc.subjectWST-1 assayen
dc.subject.ddc540
dc.titleFluorescence microscopy studies on the fibrillation of IAPP at model and cellular lipid interfaces, from mechanism to potential strategies in type II diabetes mellitusen
dc.typeText
dc.type.publicationtypedoctoralThesisde
dcterms.accessRightsopen access

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