Clinical characteristics and outcomes of diabetics hospitalized for COVID-19 infection

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dc.contributor.authorMansour, Asieh
dc.contributor.authorSajjadi-Jazi, Sayed Mahmoud
dc.contributor.authorKasaeian, Amir
dc.contributor.authorKhosravi, Bardia
dc.contributor.authorSorouri, Majid
dc.contributor.authorAzizi, Fatemeh
dc.contributor.authorRajabi, Zeinab
dc.contributor.authorMotamedi, Fatemeh
dc.contributor.authorSirusbakht, Azin
dc.contributor.authorEslahi, Masoud
dc.contributor.authorMojtabbavi, Heila
dc.contributor.authorAli Reza Sima, Ali Reza
dc.contributor.authorRadmard, Amir Reza
dc.contributor.authorMohajeri-Tehrani, Mohhamad Reza
dc.contributor.authorAbdollahi, Mohammad
dc.date.accessioned2020-12-17T14:31:36Z
dc.date.available2020-12-17T14:31:36Z
dc.date.issued2020-11-16
dc.description.abstractSome debates exist regarding the association of diabetes mellitus (DM) with COVID-19 infection severity and mortality. In this study, we aimed to describe and compare the clinical characteristics and outcomes of hospitalized COVID-19 patients with and without DM. In this single-centered, retrospective, observational study, we enrolled adult patients with COVID-19 who were admitted to the Shariati hospital, Tehran, Iran, from February 25, 2020, to April 21, 2020. The clinical and paraclinical information as well as the clinical outcomes of patients were collected from inpatient medical records. A total of 353 cases were included (mean age, 61.67 years; 57.51 % male), of whom 111 patients were diabetics (mean age, 63.66 years; 55.86 % male). In comparison to those without DM, diabetic patients with COVID-19 were more likely to have other comorbidities, elevated systolic blood pressure (SBP), elevated blood sugar (BS), lower estimated glomerular filtration rate (eGFR) and elevated blood urea nitrogen (BUN). The association of DM with severe outcomes of COVID-19 infection (i.e. mechanical ventilation, median length of hospital stay and mortality) remained non-significant before and after adjustments for several factors including age, sex, body mass index (BMI), smoking status, and comorbidities. Based on our results DM has not been associated with worse outcomes in hospitalized patients for COVID-19 infection.en
dc.identifier.citationMansour, A., Sajjadi-Jazi, S. M. ., Kasaeian, . A. ., Khosravi, . B. ., Sorouri, M. ., Azizi, F. ., Rajabi, . Z. ., Motamedi, F. ., Sirusbakht, A. ., Eslahi , M. ., Mojtabbavi, H. ., Sima, . A. R. ., Radmard, A. R. ., Mohajeri-Tehrani, M. R. ., & Abdollahi, M. . (2020). Clinical characteristics and outcomes of diabetics hospitalized for COVID-19 infection: a single-centered, retrospective, observational study. EXCLI Journal, 19, 1533-1543. https://doi.org/10.17179/excli2020-2988de
dc.identifier.issn1611-2156
dc.identifier.urihttp://hdl.handle.net/2003/39924
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-21814
dc.language.isoen
dc.publisherIfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmundde
dc.relation.ispartofseriesEXCLI Journal;Vol. 19. 2020, pp. 1533-1543
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCOVID-19en
dc.subjectDiabetes mellitusen
dc.subjectDMen
dc.subject.ddc610
dc.titleClinical characteristics and outcomes of diabetics hospitalized for COVID-19 infectionen
dc.title.alternativea single-centered, retrospective, observational studyen
dc.typeText
dc.type.publicationtypearticle
dcterms.accessRightsopen access
eldorado.dnb.zdberstkatid2132560-1
eldorado.identifier.urlhttps://www.excli.de/index.php/excli/article/view/2988
eldorado.secondarypublicationtrue

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