Pathophysiology and therapy of systemic vasculitides

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dc.contributor.authorRalli, Massimo
dc.contributor.authorCampo, Flaminia
dc.contributor.authorAngeletti, Diletta
dc.contributor.authorMinni, Antonio
dc.contributor.authorArtico, Marco
dc.contributor.authorGreco, Antonio
dc.contributor.authorPolimeni, Antonella
dc.contributor.authorde Vincentiis, Marco
dc.date.accessioned2020-12-16T15:32:13Z
dc.date.available2020-12-16T15:32:13Z
dc.date.issued2020-06-18
dc.description.abstractSystemic vasculitides represent uncommon conditions characterized by the inflammation of blood vessels that can lead to different complex disorders limited to one organ or potentially involving multiple organs and systems. Systemic vasculitides are classified according to the diameter of the vessel that they mainly affect (small, medium, large, or variable). The pathogenetic mechanisms of systemic vasculitides are still partly unknown, as well as their genetic basis. For most of the primary systemic vasculitides, a single gold standard test is not available, and diagnosis is often made after having ruled out other mimicking conditions. Current research has focused on new management protocol and therapeutic strategies aimed at improving long-term patient outcomes and avoiding progression to multiorgan failure with irreversible damage. In this narrative review, authors describe different forms of systemic vasculitides through a review of the literature, with the aim of highlighting the current knowledge and recent findings on etiopathogenesis, diagnosis and therapy.en
dc.identifier.citationRalli, M., Campo, F., Angeletti, D., Minni, A., Artico, M., Greco, A., Polimeni, A., & de Vincentiis, M. (2020). Pathophysiology and therapy of systemic vasculitides. EXCLI Journal, 19, 817-854. https://doi.org/10.17179/excli2020-2510de
dc.identifier.issn1611-2156
dc.identifier.urihttp://hdl.handle.net/2003/39907
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-21797
dc.language.isoen
dc.publisherIfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmundde
dc.relation.ispartofseriesEXCLI Journal;Vol. 19. 2020, pp. 817-854
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectSystemic vasculitidesen
dc.subjectKawasaki diseaseen
dc.subjectTakayasu arteritisen
dc.subjectPolyarteritis nodosaen
dc.subjectGiant cell arteritisen
dc.subjectBehcet’s diseaseen
dc.subject.ddc610
dc.titlePathophysiology and therapy of systemic vasculitidesen
dc.typeText
dc.type.publicationtypearticle
dcterms.accessRightsopen access
eldorado.dnb.zdberstkatid2132560-1
eldorado.dnb.zdberstkatidtrue
eldorado.identifier.urlhttps://doi.org/10.17179/excli2020-2510

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