Anticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino mice

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dc.contributor.authorAhmad, Shiekh Tanveer
dc.contributor.authorAsiaf, Asia
dc.contributor.authorAslam, Mohammad
dc.contributor.authorBhat, Jalal Uddin
dc.contributor.authorKhanam, Razia
dc.contributor.authorMujeeb, Mohammad
dc.contributor.authorNizami, Qudsia
dc.contributor.authorParray, Shabir Ahmad
dc.contributor.authorSiddiqui, Aisha
dc.contributor.authorUmar, Sadiq
dc.date.accessioned2012-09-19T13:27:14Z
dc.date.available2012-09-19T13:27:14Z
dc.date.issued2012-09-19
dc.description.abstractThe aim of the present study was to evaluate the anticonvulsant effect of whole plant extracts of Melissa parviflora using MES and PTZ induced seizures models. The dried whole plant was subjected to extraction in methanol and water. The extracts were subjected to phytochem-ical tests and the carbohydrate, flavonols, coumarins, glycosides and steroid were found to be present. The methanolic and aqueous extracts of the plant of Melissa parviflora were observed for their anticonvulsant activity by Maximal Electroshock seizures (MES) test and Pentylene-tetrazole (PTZ) test using Swiss albino mice. Both the extracts showed significant activity in MES and PTZ induced convulsions in comparison to control. From the literature surveys as well experiments performed, it can be said that Melissa parviflora does pose anticonvulsant property.en
dc.identifier.issn1611-2156
dc.identifier.urihttp://hdl.handle.net/2003/29620
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-4921
dc.language.isoende
dc.relation.ispartofseriesEXCLI Journal ; Vol. 11, 2012en
dc.subjectanticonvulsant effectsen
dc.subjectmaximal electroshocken
dc.subjectMelissa parvifloraen
dc.subjectpentylene-tetrazoleen
dc.subject.ddc610
dc.titleAnticonvulsant activity of methanolic and aqueous extracts of Melissa parviflora in experimentally induced Swiss albino miceen
dc.typeTextde
dc.type.publicationtypearticlede
dcterms.accessRightsopen access
eldorado.dnb.zdberstkatid2132560-1

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