Expression of the protein phosphatases PP1a and PP1g1 in rat ascites hepatoma cell lines and in rat hepatocyte cell line

dc.contributor.author	Kikuchi, Kunimi	de
dc.contributor.author	Saadat, Mostafa	de
dc.date.accessioned	2008-06-17T13:58:49Z
dc.date.available	2008-06-17T13:58:49Z
dc.date.issued	2005-10-10	de
dc.description.abstract	Expressions of protein phosphatases 1a (PP1a), and 1g1 (PP1g1) was determined in cultured rat ascites hepatoma cell lines (AH-13, AH-109A) and in the normal rat hepatocyte cell line RLN-B2 by Northern blot analysis. High levels of PP1a mRNA expression were observed only in the hepatoma cells. In RLN-B2 cells only PP1g1 mRNA was increased compared to normal rat liver. In all cell types, mRNA levels of PP1g1 decreased as a function of harvest time. The present data show that PP1a mRNA is expressed at high levels in hepatoma cells in vivo, but rapidly decreased under critical nutritional conditions.	en
dc.identifier.issn	1611-2156	de
dc.identifier.uri	http://hdl.handle.net/2003/25653
dc.identifier.uri	http://dx.doi.org/10.17877/DE290R-340
dc.language.iso	en	de
dc.relation.ispartofseries	EXCLI Journal ; Vol. 4, 2005	en
dc.subject	ascites hepatoma	en
dc.subject	cell culture	en
dc.subject	PP1a	en
dc.subject	PP1g1	en
dc.subject	protein phosphatase	en
dc.subject.ddc	610
dc.title	Expression of the protein phosphatases PP1a and PP1g1 in rat ascites hepatoma cell lines and in rat hepatocyte cell line	en
dc.type	Text	de
dc.type.publicationtype	article	de
dcterms.accessRights	open access
eldorado.dnb.zdberstkatid	2132560-1

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