Natural products as reservoirs of novel therapeutic agents
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Date
2018-05-04
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Abstract
Since ancient times, natural products from plants, animals, microbial and marine sources have been exploited for
treatment of several diseases. The knowledge of our ancestors is the base of modern drug discovery process. However,
due to the presence of extensive biodiversity in natural sources, the percentage of secondary metabolites
screened for bioactivity is low. This review aims to provide a brief overview of historically significant natural
therapeutic agents along with some current potential drug candidates. It will also provide an insight into pros and
cons of natural product discovery and how development of recent approaches has answered the challenges associated
with it.
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Keywords
Bioactive, Secondary metabolites, Plants, Animals, Marine organisms, Microbes