Atrial natriuretic peptide gene - a potential biomarker for Long QT syndrome
| dc.contributor.author | Qureshi, Sameera Fatima | |
| dc.contributor.author | Ali, Altaf | |
| dc.contributor.author | Venkateshwari, Ananthapur | |
| dc.contributor.author | Rao, Hygriv | |
| dc.contributor.author | Jayakrishnan, M. P. | |
| dc.contributor.author | Narasimhan, Calambur | |
| dc.contributor.author | Shenthar, Jayaprakash | |
| dc.contributor.author | Thangaraj, Kumarasamy | |
| dc.contributor.author | Nallari, Pratibha | |
| dc.date.accessioned | 2014-11-25T10:05:01Z | |
| dc.date.available | 2014-11-25T10:05:01Z | |
| dc.date.issued | 2014-08-15 | |
| dc.description.abstract | This study highlights the possible implication of NPPA (natriuretic peptide precursor A) gene in the etiology of Long QT syndrome (LQTS) by population-based as well as familial study. Three SNPs of NPPA- C-664G, C1363A and T1766C were examined by molecular analyses in LQTS, controls and first degree relatives (FDRs). This study revealed a possible association of 1364 C>A SNP āCā allele with LQTS (p = 0.0013). All three SNPs were in tight linkage disequilibrium. The familial study highlights the association of NPPA SNP with cLQTS and implicating it as a potential biomarker in South Indian population. | en |
| dc.identifier.issn | 1611-2156 | |
| dc.identifier.uri | http://hdl.handle.net/2003/33699 | |
| dc.identifier.uri | http://dx.doi.org/10.17877/DE290R-6728 | |
| dc.language.iso | en | |
| dc.relation.ispartofseries | EXCLI Journal ; Vol. 13, 2014 | en |
| dc.subject | atrial natriuretic peptide | en |
| dc.subject | Long QT syndrome | en |
| dc.subject | cardiogenesis | en |
| dc.subject | biomarker | en |
| dc.subject | polymorphisms | en |
| dc.subject.ddc | 610 | |
| dc.title | Atrial natriuretic peptide gene - a potential biomarker for Long QT syndrome | en |
| dc.type | Text | |
| dc.type.publicationtype | article | |
| dcterms.accessRights | open access | |
| eldorado.dnb.zdberstkatid | 2132560-1 |