Antifungal potential of essential oil and ethanol extracts of Lonicera japonica Thunb. against dermatophytes

dc.contributor.authorRahman, Atiqur
dc.contributor.authorAl-Reza, Sharif M.
dc.contributor.authorSiddiqui, Shah Alam
dc.contributor.authorChang, Taehyun
dc.contributor.authorKang, Sun Chul
dc.date.accessioned2014-07-24T09:00:39Z
dc.date.available2014-07-24T09:00:39Z
dc.date.issued2014-04-28
dc.description.abstractThe antifungal potential of essential oil and ethanolic leaf extracts of Lonicera japonica Thunb. was evaluated for controlling the growth of dermatophytes. The oil (1,000 ppm) and extracts (1,500 ppm) of L. japonica revealed 55.1–70.3 % and 40.1–65.5 % antidermatophytic effect against Microsporum canis KCTC 6348, 6349, 6591, Trichophyton rubrum KCTC 6345, 6352, 6375, Trichophyton mentagrophytes KCTC 6077 and 6085, respectively, along with their respective minimum inhibitory concentrations ranging from 62.5-500 and 125-1,000 μg/ml. Also, the oil had strong detrimental effect on spore germination of all the tested dermatophytes as well as concentration and time-dependent kinetic inhibition of M. canis KCTC 6348. The results demonstrated that L. japonica oil and extracts could be potential sources of natural fungicides to protect human and animals from fungal infections.en
dc.identifier.issn1611-2156
dc.identifier.urihttp://hdl.handle.net/2003/33526
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-15589
dc.language.isoen
dc.relation.ispartofseriesEXCLI Journal ; Vol. 13, 2014en
dc.subjectLonicera japonica Thunb.en
dc.subjectessential oilen
dc.subjectethanolic extractsen
dc.subjectantidermatophytic activityen
dc.subjectskin infectious fungal pathogensen
dc.subject.ddc610
dc.titleAntifungal potential of essential oil and ethanol extracts of Lonicera japonica Thunb. against dermatophytesen
dc.typeText
dc.type.publicationtypearticle
dcterms.accessRightsopen access
eldorado.dnb.zdberstkatid2132560-1

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