Larvicidal activity and structure activity relationship of cinnamoyl amides from Zanthoxylum armatum and their synthetic analogues against diamondback moth, Plutella xylostella
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Date
2016-03-18
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Abstract
Cinnamoyl amides isolated from Zanthoxylum armatum (Rutaceae) and their synthetic analogues were tested for their insecticidal activity against the second instar larvae of diamondback moth, Plutella xylostella (L.) (Lepidoptera: Yponomeutidae) to determine the promising structures with insecticidal activity. Most of the test compounds showed promising activity against larvae of P. xylostella. However, the activities of different compounds varied depending on the presence of different substituents at various positions of both the aromatic rings A and B. Among the tested compounds, 8, N-(3-bromo-4-methoxyphenethyl)cinnamamide showed best larvicidal activity with an LC50 = 62.13 mg/L followed by 6, N-(3 ׳-bromophenethyl)cinnamamide (LC50=128.49 mg/L) and 2 N-(4 ׳-methoxyphenylethyl)cinnamamide (LC50 = 225.65 mg/L).
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Keywords
cinnamoyl amides, structure activity relationship, larvicidal activity, Plutella xylostella