Cordyceps sinensis biomass produced by submerged fermentation in high-fat diet feed rats normalizes the blood lipid and the low testosterone induced by diet

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dc.contributor.authorAikawa, Júlia
dc.contributor.authorBonatto, Sandro José Ribeiro
dc.contributor.authorFreire dos Santos, Leandro
dc.contributor.authorHabu, Sascha
dc.contributor.authorPrado, Karin Braun
dc.contributor.authorRubel, Rosália
dc.contributor.authorSoccol, Carlos Ricardo
dc.contributor.authorSoccol, Vanete Thomaz
dc.contributor.authorTorres, Maria Fernanda
dc.contributor.authorYamaguchi, Adriana Aya
dc.contributor.authorZanatta, Ana Lucia
dc.date.accessioned2013-05-13T11:00:13Z
dc.date.available2013-05-13T11:00:13Z
dc.date.issued2013-05-13
dc.description.abstractThis study investigated the effect of Cordyceps sinensis biomass supplementation obtained from submerged fermentation on blood lipid and low testosterone induced by high-fat diet (HFD). The experiments were carried out using a long-term intake of HFD and HFD plus Simvastatin or C. sinensis (4 months). Our results show that plasma cholesterol, triglycerides and LDL were decreased by Cordyceps sinensis biomass supplementation (CSBS). A longterm intake of HFD caused a significant liver damage which has been reverted by CSBS. CSBS normalized decreasing testosterone levels observed in high-fat diet feed rats. All these findings lead us to suggest that C. sinensis was able to decrease blood lipid concentration, increase hepatoprotective activity and normalize testosterone levels.en
dc.identifier.issn1611-2156
dc.identifier.urihttp://hdl.handle.net/2003/30314
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-10558
dc.language.isoende
dc.relation.ispartofseriesEXCLI Journal ; Vol. 11, 2012en
dc.subjectCordyceps sinensisen
dc.subjecthigh-fat dieten
dc.subjecthypolipidemic effecten
dc.subjecttestosteroneen
dc.subject.ddc610
dc.titleCordyceps sinensis biomass produced by submerged fermentation in high-fat diet feed rats normalizes the blood lipid and the low testosterone induced by dieten
dc.typeTextde
dc.type.publicationtypearticlede
dcterms.accessRightsopen access
eldorado.dnb.zdberstkatid2132560-1

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