Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia

dc.contributor.author	Da, Wan Ming
dc.contributor.author	Fan, Hui
dc.contributor.author	Guo, Bo
dc.contributor.author	Li, Su Xia
dc.contributor.author	Lu, Xue Chun
dc.contributor.author	Zhu, Hong Li
dc.date.accessioned	2012-09-19T12:57:47Z
dc.date.available	2012-09-19T12:57:47Z
dc.date.issued	2012-09-19
dc.description.abstract	Cytogenetic abnormalities are frequently detected in patients with acute lymphoblastic leu-kemia (ALL). Comprehensive karyotype was related to poor prognosis frequently in ALL. We present a comprehensive karyotype in an adult ALL by spectral karyotyping (SKY) and R-banding. SKY not only confirmed the abnormalities previously seen by R-banding but also improved comprehensive karyotype analysis with the following result 47,XY,+9, ins(1;5)(q23;q23q34) t(6;7)(q23;p13). Our report demonstrated that SKY is able to provide more information accurately for prediction of disease prognosis in adult ALL with compre-hensive karyotype.	en
dc.identifier.issn	1611-2156
dc.identifier.uri	http://hdl.handle.net/2003/29612
dc.identifier.uri	http://dx.doi.org/10.17877/DE290R-4930
dc.language.iso	en	de
dc.relation.ispartofseries	EXCLI Journal ; Vol. 11, 2012	en
dc.subject	acute lymphoblastic leukemia	en
dc.subject	comprehensive karyotype	en
dc.subject	SKY	de
dc.subject.ddc	610
dc.title	Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia	en
dc.type	Text	de
dc.type.publicationtype	article	de
dcterms.accessRights	open access
eldorado.dnb.deposit	true
eldorado.dnb.zdberstkatid	2132560-1

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