Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia

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dc.contributor.authorDa, Wan Ming
dc.contributor.authorFan, Hui
dc.contributor.authorGuo, Bo
dc.contributor.authorLi, Su Xia
dc.contributor.authorLu, Xue Chun
dc.contributor.authorZhu, Hong Li
dc.date.accessioned2012-09-19T12:57:47Z
dc.date.available2012-09-19T12:57:47Z
dc.date.issued2012-09-19
dc.description.abstractCytogenetic abnormalities are frequently detected in patients with acute lymphoblastic leu-kemia (ALL). Comprehensive karyotype was related to poor prognosis frequently in ALL. We present a comprehensive karyotype in an adult ALL by spectral karyotyping (SKY) and R-banding. SKY not only confirmed the abnormalities previously seen by R-banding but also improved comprehensive karyotype analysis with the following result 47,XY,+9, ins(1;5)(q23;q23q34) t(6;7)(q23;p13). Our report demonstrated that SKY is able to provide more information accurately for prediction of disease prognosis in adult ALL with compre-hensive karyotype.en
dc.identifier.issn1611-2156
dc.identifier.urihttp://hdl.handle.net/2003/29612
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-4930
dc.language.isoende
dc.relation.ispartofseriesEXCLI Journal ; Vol. 11, 2012en
dc.subjectacute lymphoblastic leukemiaen
dc.subjectcomprehensive karyotypeen
dc.subjectSKYde
dc.subject.ddc610
dc.titleSpectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemiaen
dc.typeTextde
dc.type.publicationtypearticlede
dcterms.accessRightsopen access
eldorado.dnb.zdberstkatid2132560-1

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