Homogeneous catalysis at its edge: high-temperature Ru-catalysed amination of alcohols under continuous flow conditions
Loading...
Date
2023-01-20
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Combining a tubular flow reactor with a robust homogeneous catalyst enabled running the alcohol amination at unique conditions, i. e., very high temperatures at low residence times. Catalytic activities were thus increased to unprecedented values of >900 h−1 in the synthesis of tertiary dimethylalkylamines directly from alcohols with excellent selectivities exceeding 99 %. Furthermore, several alcohols could be converted to the desired tertiary amines.
Description
Table of contents
Keywords
Homogeneous catalysis, Flow chemistry, Amine synthesis