COVID-19 pandemic and student reading achievement: findings from a school panel study See

Since 2020, the COVID-19 pandemic had an impact on education worldwide. There is increased discussion of possible negative effects on students’ learning outcomes and the need for targeted support. We examined fourth graders’ reading achievement based on a school panel study, representative on the student level, with N = 111 elementary schools in Germany (total: N = 4,290 students, age: 9–10 years). The students were tested with the Progress in International Reading Literacy Study instruments ...

Praktiken des Komponierens mit Loops und Samples See

Heteroleptische Dirhodium(II)-Komplexe und ihre Rolle als Katalysatoren in der asymmetrischen Cyclopropanierung mit α-metallierten Diazoverbindungen See

Die asymmetrische, intermolekulare Cyclopropanierung mit α-metallierten Diazoverbindungen ermöglicht die Darstellung von stereodefinierten α-metallierten Cyclopropanen. Diese sind wertvolle Bausteine für die Darstellung von Enantiomeren-angereicherten, strukturell vielfältigen Cyclopropanen. Ein neuartiger heteroleptische Dirhodium(II)-Komplex mit einem Amidat-Liganden weist eine einzigartige Reaktivität als Katalysator in dieser Cyclopropanierungsreaktion auf. Ursprünglich wurde dieser als V...

Labordidaktik in the making See

In den der kumulativen Dissertation zugrundeliegenden labordidaktischen Forschungsarbeiten wurden folgende drei übergeordneten Forschungsfragen bearbeitet: Vor welchen aktuellen und zukünftigen Herausforderungen steht das Lehren und Lernen in ingenieurwissenschaftlichen Fachlaboren? Wie lässt sich das Lehren und Lernen in den Fachlaboren theoretisch fassen und empirisch untersuchen? Wie lässt sich die Laborlehre anwendungs- und kompetenzorientierter gestalten, um den identifizierten Herausfor...

Local thermodynamic characterisation of binding sites and protein-ligand interactions See

With the advent of high-performance computing and progress in fields like structural biology, structure-based drug design (SBDD) has become an essential part in drug discovery projects. Yet, the automated de novo design of the “perfect” ligand to a protein structure remains unreached, even with today’s (re)emergence of powerful machine learning techniques. One of the reasons for this is the difficulty to consider all thermodynamically relevant details of protein-ligand complex formation in th...

Personal resources and leadership behavior See

This dissertation examines the role of leaders’ personal resources in the work-related context. The main goal is to explore the influence of leaders’ mindfulness and resilience on leadership behavior and employees’ work-related outcomes based on the integrative framework by Good et al. (2016). The first study explores leaders’ mindfulness and resilience as potential antecedents of servant and destructive leadership and the mediating effect of these leadership behaviors regarding employees’ tr...

Die Erhebung, Operationalisierung und Analyse von Aktionsräumen unter Nutzung von Befragungen See

Aktionsräume geben Aufschluss über die Nutzung räumlicher Infrastrukturen im Rahmen individueller Mobilität und eignen sich für vielfältige Untersuchungen über Wechselwirkungen zwischen Menschen und ihrer sozialen sowie räumlichen Umwelt. In quantitativen Erhebungen werden Aktionsräume unter anderem über Wegetagebücher, Tracking-Verfahren und Befragungen erfasst. Tracking-Verfahren und Wegetagebücher sind zwar präzise Instrumente zur Erfassung individueller Bewegungsmuster, erfordern für komp...

The silicon strip detector of the ATLAS Inner Tracker: from individual sensing units to multi-module petal structures See

Nowadays particle detector technology is taking big steps forwards and new devices dedicated to particle physics show very high performance. Particularly the semiconductor detectors have advanced significantly and are used for tracking purposes in the A Toroidal LHC ApparatuS (ATLAS) experiment at CERN thanks to their excellent spacial resolution: the compact size of the silicon and its high granularity allow to reach a precision measurement of few tens of microns. This thesis is focuse...

Models, unification, and simulations: Margaret C. Morrison (1954–2021) See

The philosophy of science community mourns the loss of Margaret Catherine Morrison, who passed away on January 9, 2021, after a long battle with cancer. Margie, as she was known to all who knew her, was highly regarded for her influential contributions to the philosophy of science, particularly her studies of the role of models and simulations in the natural and social sciences. These contributions made her a world-leading philosopher of science, instrumental in shifting philosophers' attenti...

Cross-cultural differences in academic self-efficacy and its sources across socialization contexts See

This study investigated how as reported by Bandura (Self-efficacy: The exercise of control Freeman, 1997) sources of self-efficacy differ across socialization contexts for German students with diverse immigrant backgrounds. We measured all four sources of academic self-efficacy in three socialization contexts for students of former Soviet Union and Turkish descent as well as without an immigrant background, assuming that we would find differences between these groups. Participants were 1217 s...

Potential impact assessment of climate-related hazards on urban public health services: interaction of changing climate-related hazards and urban development in the future, Khon Kaen City, Thailand See

Current understanding of the interactions between the future urban development change and climate change in the local context, considering infrastructure operation & functionality, is still primitive, especially in public health services. This study offers a climate-resilient operationalization framework for urban public health services considering the interaction between urban development change and climate change across scales, the so-called Health Integrative Climate Resilience and Adaptat...

Erwerb von vernetztem professionellem Wissen über Rechtschreibunterricht im Lehramtsstudium See

In der Professionalisierung von Deutschlehrkräften gelingt es nur mäßig Fachwissen und fachdidaktisches Wissen in der universitären Ausbildungsphase zu vermitteln. Zudem gelingt der Zugriff von Studierenden auf erworbenes Wissen in fachdidaktischen Anforderungssituationen kaum. Lehramtsstudierende sollen ein vernetztes professionelles Wissen aufbauen, um in professionellen Handlungssituationen explizit auf die Wissensinhalte zugreifen zu können. Ob der Aufbau solch eines Professionswissens in...

Exercise reduces systemic immune inflammation index (SII) in childhood cancer patients See

While exercise and physical activity have been suggested to reduce mortality and symptoms in cancer, knowledge on these associations in patients with childhood cancer (CCPs) is sparse. Anti-inflammatory properties of exercise might mediate these beneficial effects. We investigated the influence of exercise on the inflammation markers neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and systemic-immune-inflammation index (SII) and associations to patient-reported-outcomes in CCPs ...

On the correspondence between abstract dialectical frameworks and nonmonotonic conditional logics See

The exact relationship between formal argumentation and nonmonotonic logics is a research topic that keeps on eluding researchers despite recent intensified efforts. We contribute to a deeper understanding of this relation by investigating characterizations of abstract dialectical frameworks in conditional logics for nonmonotonic reasoning. We first show that in general, there is a gap between argumentation and conditional semantics when applying several intuitive translations, but then prove...

A finite deformation electro-mechanically coupled computational multiscale formulation for electrical conductors See

Motivated by the influence of deformation-induced microcracks on the effective electrical properties at the macroscale, an electro-mechanically coupled computational multiscale formulation for electrical conductors is proposed. The formulation accounts for finite deformation processes and is a direct extension of the fundamental theoretical developments presented by Kaiser and Menzel (Arch Appl Mech 91:1509–1526, 2021) who assume a geometrically linearised setting. More specifically speaking,...

Wegner estimate for random divergence-type operators monotone in the randomness See

In this note, a Wegner estimate for random divergence-type operators that are monotone in the randomness is proven. The proof is based on a recently shown unique continuation estimate for the gradient and the ensuing eigenvalue liftings. The random model which is studied here contains quite general random perturbations, among others, some that have a non-linear dependence on the random parameters.

Research on economic planning and operation of electric vehicle charging stations See

Appropriately planning and scheduling strategies can improve the enthusiasm of Electric vehicles (EVs), reduce charging losses, and support the power grid system. Thus, this dissertation studies the planning and operating of the EV charging station. First, an EV charging station planning strategy considering the overall social cost is proposed. Then, to reduce the charging cost and guarantee the charging demand, an optimal charging scheduling method is proposed. Additionally, by considering t...

Discovery and characterization of Pun1p, a putative component of the yeast fertilization synapse See

Cell-cell fusion is a fundamental process in sexual reproduction and development but the mechanisms mediating and regulating this process are only now beginning to be uncovered. Despite recent progress in identifying key players in the plant and protist kingdoms, large gaps remain in other Eukaryotic lineages, including fungi. The cell fusion in the mating of the yeast Saccharomyces cerevisiae therefore presents itself as an ideal system to understand the molecular mechanisms underlying cell ...

Strukturbiologische und zelluläre Charakterisierung Isoform-selektiver kovalent-allosterischer Akt-Inhibitoren See

Die Proteinkinase Akt, die aus drei Isoformen (Akt1/Akt2/Akt3) besteht, ist ein zentraler Knotenpunkt innerhalb des PI3K/Akt/mTOR-Signalwegs. Genomische Veränderungen wie aktivierende Mutationen in PI3K und Amplifikationen von AKT-Genen können eine Überaktivierung der Akt-Isoformen und damit einhergehend verschiedene Krankheiten auslösen. Trotz intensiver Forschung in den letzten Jahrzehnten sind mehrere klinische Studien mit potenziellen Arzneimittelkandidaten gescheitert. Verantwortlich daf...