Authors: Aikawa, Júlia
Bonatto, Sandro José Ribeiro
Freire dos Santos, Leandro
Habu, Sascha
Prado, Karin Braun
Rubel, Rosália
Soccol, Carlos Ricardo
Soccol, Vanete Thomaz
Torres, Maria Fernanda
Yamaguchi, Adriana Aya
Zanatta, Ana Lucia
Title: Cordyceps sinensis biomass produced by submerged fermentation in high-fat diet feed rats normalizes the blood lipid and the low testosterone induced by diet
Language (ISO): en
Abstract: This study investigated the effect of Cordyceps sinensis biomass supplementation obtained from submerged fermentation on blood lipid and low testosterone induced by high-fat diet (HFD). The experiments were carried out using a long-term intake of HFD and HFD plus Simvastatin or C. sinensis (4 months). Our results show that plasma cholesterol, triglycerides and LDL were decreased by Cordyceps sinensis biomass supplementation (CSBS). A longterm intake of HFD caused a significant liver damage which has been reverted by CSBS. CSBS normalized decreasing testosterone levels observed in high-fat diet feed rats. All these findings lead us to suggest that C. sinensis was able to decrease blood lipid concentration, increase hepatoprotective activity and normalize testosterone levels.
Subject Headings: Cordyceps sinensis
high-fat diet
hypolipidemic effect
Issue Date: 2013-05-13
Appears in Collections:Original Articles

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