Authors: Emrich, K.
Urfer, W.
Title: Estimation of genetic parameters using molecular markers and EM-algorithms
Language (ISO): en
Abstract: In this paper we present a new method for estimating genetic parameters of an F2-generation model. Using an iterative algorithm we derive explicit expressions for the Maximum Likelihood estimates of the additive and dominance effects. Finally we calculate the variance covariance matrix of our Maximum Likelihood estimates, which enables us to determine a confidence interval for the location of a quantitative trait locus.
Subject Headings: confidence intervals for genetic parameters
EM and ECM-algorithms
maximum likelihood estimation
molecular genetics
variance-and covariance matrix of Maximum Likelihood estimates
URI: http://hdl.handle.net/2003/4940
http://dx.doi.org/10.17877/DE290R-6639
Issue Date: 1999
Publisher: Universitätsbibliothek Dortmund
Appears in Collections:Sonderforschungsbereich (SFB) 475

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