Authors: Brunnert, Marcus
Mevissen, Heinz-Theodor
Thiele, Ralf
Urfer, Wolfgang
Title: Statistical analysis of Sequence-Structure Alignment Scores
Language (ISO): en
Abstract: The structural analysis of proteins is fundamental to the analysis of protein functions. In this context, sequence-structure alignment methods are important among the different empirical methods. In order to assess the quality of sequence-structure alignments, a statistical method using a Bayesian approach proposed by Lathrop et al. (1998) will be presented. Finally, the results of a developed statistical analysis of scores of RDP(recursive dynamic programming)-sequence-structure alignments (Thiele et al., 1999) according to data of six proteins will be described.
Subject Headings: sequence-structure-alignment
statistically significant scores
combined Bayesian approach and RDP-alignment
Issue Date: 2002
Provenance: Universitätsbibliothek Dortmund
Appears in Collections:Sonderforschungsbereich (SFB) 475

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