Antioxidant Properties of Propofol

Astuto, Marinella; Attaguile, Giuseppa; Di Giacomo, Claudia; Gullo, Antonino; Murabito, Paolo; Rodella, Luigi F.; Volti, Giovanni Li

Antioxidant Properties of Propofol

dc.contributor.author	Astuto, Marinella	de
dc.contributor.author	Attaguile, Giuseppa	de
dc.contributor.author	Di Giacomo, Claudia	de
dc.contributor.author	Gullo, Antonino	de
dc.contributor.author	Murabito, Paolo	de
dc.contributor.author	Rodella, Luigi F.	de
dc.contributor.author	Volti, Giovanni Li	de
dc.date.accessioned	2008-06-17T14:07:34Z
dc.date.available	2008-06-17T14:07:34Z
dc.date.issued	2006-04-13	de
dc.description.abstract	Propofol is an intravenous sedative-hypnotic agent indicated for induction and maintenance of general anesthesia as well as for sedation of intubated, mechanically ventilated adults in intensive care units (ICU). Propofol is characterized by a phenolic structure similar to that of a-tocopherol, and presents antioxidant properties that have been demonstrated both in vitro and in vivo. The aim of the present review is to evaluate the antioxidant properties of propofol in various models and whether or not it may be considered an efficient therapeutic tool in counteracting oxidative stress during general anesthesia and sedation in ICU.	en
dc.identifier.issn	1611-2156	de
dc.identifier.uri	http://hdl.handle.net/2003/25672
dc.identifier.uri	http://dx.doi.org/10.17877/DE290R-7980
dc.language.iso	en	de
dc.relation.ispartofseries	EXCLI Journal ; Vol. 5, 2006	en
dc.subject	anesthesia	en
dc.subject	antioxidants	en
dc.subject	oxidative stress	en
dc.subject	polyphenols	en
dc.subject	propofol	en
dc.subject.ddc	610
dc.title	Antioxidant Properties of Propofol	en
dc.title.alternative	when oxidative stress sleeps with patients	en
dc.type	Text	de
dc.type.publicationtype	article	de
dcterms.accessRights	open access
eldorado.dnb.zdberstkatid	2132560-1

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