Magnetic and optical anisotropy of Clostridium pasteurianum rubredoxin from optically detected electron paramagnetic resonance

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Date

2001-12-01

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American Institute of Physics

Abstract

The high-spin Fe(III)-center of oxidized rubredoxin from Clostridium pasteurianum shows a complicated, temperature-dependent EPR spectrum. We combine conventional EPR spectroscopy with optically detected EPR (ODEPR) to elucidate the electronic structure of this protein metal center. The ODEPR experiment, which can be considered as coherent Raman scattering or modulated magnetic circular dichroism (MCD), yields spectra that depend on the relative orientation of optical and magnetic dipole moments. A detailed analysis of the spectra shows that they correspond to a zero-field splitting of D = +46.3 GHz and a strong rhombic distortion with E/D = 0.25. In the frozen solution, conformational strain gives rise to variation of the rhombicity, which can be measured quantitatively from the EPR line shape. Analysis of the ODEPR line shapes yields the orientation of the optical anisotropy with respect to the magnetic g-tensor. We compare the results from this study to published results on EPR, optical spectroscopy, and MCD.

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Birgit Börger and Dieter Suter: Magnetic and optical anisotropy of Clostridium pasteurianum rubredoxin from optically detected electron paramagnetic resonance. In: J. Chem. Phys. 115, 9821-9826 (2001).