Chemical constituents and anti-inflammatory activity of leaf essential oil of Nigerian grown Chenopodium album L.
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Date
2011-05-17
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Abstract
Hydrodistilled leaves of Chenopodium album yielded 0.64 % v/w of essential oil. GC and
GC/MS analyses of the oil revealed that the bulk of the oil was constituted by aromatic compounds (60.1 %). The abundant constituents of the oil were: p- cymene (40.9 %), ascaridole (15.5 %), pinane-2-ol (9.9 %), α-pinene (7.0 %), β-pinene (6.2 %) and α-terpineol (6.2 %). The oil displayed strong anti-inflammatory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA) – induced ear edema in mice.
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Keywords
anti-inflammatory, ascaridole, chenopodiaceae, Chenopodium album, p-cymene, pinane-2-ol, α-terpineol