Advanced numerical treatment of chemotaxis driven PDEs in mathematical biology

dc.contributor.advisorTurek, Stefan
dc.contributor.authorStrehl, Robert
dc.contributor.refereeBlum, Heribert
dc.date.accepted2013-07-18
dc.date.accessioned2013-08-06T05:29:47Z
dc.date.available2013-08-06T05:29:47Z
dc.date.issued2013-08-06
dc.description.abstractFrom the first formulation of chemotaxis-driven partial differential equations (PDEs) by Keller and Segel in the 1970's up to the present, much effort has been expended in modelling complex chemotaxis re- lated processes. The shear complexity of such resulting PDEs crucially limits the postulation of analytical results. In this context the sup- port by numerical tools are of utmost interest and, thus, render the implementation of a numerically well elaborated solver an undoubt- edly important task. In this work I present different iteration strategies (linear/nonlinear, decoupled/monolithic) for chemotaxis-driven PDEs. The discretiza- tion follows the method of lines, where I employ finite elements to resolve the spatial discretization. I extensively study the numerical efficiency of the iteration strategies by applying them on particular chemotaxis models. Moreover, I demonstrate the need of numerical stabilization of chemotaxis-driven PDEs and apply a exible scalar algebraic ux correction. This methodology preserves the positivity of the fully discretized scheme under mild conditions and renders the numerical solution non-oscillatory at a low level of additional compu- tational costs. This work provides a first detailed study of accurate, efficient and exible finite element schemes for chemotaxis-driven PDEs and the implemented numerical framework provides a valuable basis for fu- ture applications of the solvers to more complex models.
dc.identifier.urihttp://hdl.handle.net/2003/30452
dc.identifier.urihttp://dx.doi.org/10.17877/DE290R-10675
dc.language.isoende
dc.subjectAlgebraic flux correctionen
dc.subjectBlow upen
dc.subjectChemotaxisen
dc.subjectFinite elementsen
dc.subjectNumerical efficiencyen
dc.subjectStabilizationen
dc.subject.ddc510
dc.titleAdvanced numerical treatment of chemotaxis driven PDEs in mathematical biologyen
dc.typeTextde
dc.type.publicationtypedoctoralThesisde
dcterms.accessRightsopen access

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