Grapes contain different polyphenols and might prevent inflammation by reducing Nitric Oxide (NO) inactivation through antioxidative enzymes. The aim of this article was to demonstrate the effects of grape polyphenols on the selected inflammatory mediators, such as interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-a), and high-sensitivity C-reactive protein (hs-CRP). To find papers assessing the effects of grape polyphenols on inflammatory mediators, electronic data bases, including ISI ...

As of today, personalized item suggestions provided by an automated recommender system have become a crucial part of many online services, e.g., online shops or media streaming applications, and extensive evidence exists that such systems increase both the user experience as well as the revenue of the providers. In academia, the recommendation problem is often framed as finding suitable items that a user is not yet aware of based on his long-term preference profile. In the real world, however...

In der vorliegenden Arbeit wird, basierend auf der Finiten-Elemente-Methode, ein numerisches Verfahren zur Lösung von dynamischen, thermomechanisch gekoppelten, elastoplastischen und reibungsbehafteten Kontaktproblemen entwickelt. In dem betrachteten Modellproblem werden die linearisierte Kontaktbedingungen und Verzerrungen verwendet, jedoch wird für die plastische Verzerrung sowohl kinematische als auch isotropische Verfestigung berücksichtigt. Als Reibgrenze werden allgemeine Reibgesetze zu...

As immigration to Europe has increased, so has support for extremist parties. While many studies have examined the effect of immigration on election outcomes, few have probed the effect of asylum seekers – those fleeing strife and persecution – on voting, nor has there been much research on the mediating role of local economic conditions. Drawing on county level panel data from Germany, our study fills both gaps. We find that economic circumstances, as measured by the unemployment rate a...

Natural Killer (NK) cells act as the front line of the body´s defense in the immune system and they are key players in efficiently recognizing and eliminating virus-infected and tumor cells. Individual NK cells can eliminate multiple target cells in a sequential manner during a process named serial killing. There are two major pathways NK cells use to induce apoptosis in their target cells: By releasing the content of cytotoxic granules containing the serine protease granzyme B (GrzB) and the...

In this work, we present a new approach for coupled CFD-optics problems that consists of a combination of a finite element method (FEM) based flow solver with a ray tracing based tool for optic forces that are induced by a laser. We combined the open-source computational fluid dynamics (CFD) package FEATFLOW with the ray tracing software of the LAT-RUB to simulate optical trap configurations. We benchmark and analyze the solver first based on a configuration with a single spherical particle t...

Nitrogen-vacancy (NV) centers in diamond have become an important tool for quantumtechnologies. All of these applications rely on long coherence times of electron and nuclear spinsassociated with these centers. Here, we study the energy level anti-crossings of an NV center indiamond coupled to a first-shell13C nuclear spin in a small static magnetic field. These levelanti-crossings (LACs) occur for specific orientations of the static magnetic field due to the strongnon-secular components of t...

Large data sets are often stored distributedly to increase the reliability of systems and the efficiency of query evaluation in them. While some query operators -- like selections and projections -- are intrinsically conform with parallel evaluation, others -- like joins -- demand specific distribution patterns. For relational databases, a common approach to evaluate queries in parallel relies on the use of rather simple distribution patterns for binary joins and the computation of the que...