Autor(en): | Da, Wan Ming Fan, Hui Guo, Bo Li, Su Xia Lu, Xue Chun Zhu, Hong Li |
Titel: | Spectral karyotyping reveals a comprehensive karyotype in an adult acute lymphoblastic leukemia |
Sprache (ISO): | en |
Zusammenfassung: | Cytogenetic abnormalities are frequently detected in patients with acute lymphoblastic leu-kemia (ALL). Comprehensive karyotype was related to poor prognosis frequently in ALL. We present a comprehensive karyotype in an adult ALL by spectral karyotyping (SKY) and R-banding. SKY not only confirmed the abnormalities previously seen by R-banding but also improved comprehensive karyotype analysis with the following result 47,XY,+9, ins(1;5)(q23;q23q34) t(6;7)(q23;p13). Our report demonstrated that SKY is able to provide more information accurately for prediction of disease prognosis in adult ALL with compre-hensive karyotype. |
Schlagwörter: | acute lymphoblastic leukemia comprehensive karyotype SKY |
URI: | http://hdl.handle.net/2003/29612 http://dx.doi.org/10.17877/DE290R-4930 |
Erscheinungsdatum: | 2012-09-19 |
Enthalten in den Sammlungen: | Case Reports |
Dateien zu dieser Ressource:
Datei | Beschreibung | Größe | Format | |
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Zhu_01032012_proof.pdf | DNB | 276.1 kB | Adobe PDF | Öffnen/Anzeigen |
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